In our Isaiah passage it is clear that God is sovereign and in complete control of everything that happens. He can cause leaders and nations to rise and fall as He wills it - in either blessing or discipline or wrath.
The section on women and their obsession with their outward appearance is definitely applicable today! When we become obsessed with our outer beauty alone, we reflect the moral decay of the nation and ultimately, detract from the glory of God. We are not to try to attract attention based on our looks but rather pursue purity of heart in order to give God glory.
A few things stood out to me in the Mark passage...
The disciples didn't understand why Jesus wasn't on a mission to continue healing everyone, but they didn't realize that His true mission was to preach the gospel. Obviously, it is good for us to help those in need, to serve the poor, to visit the sick. But all that is really useless without the good news. We cannot become so consumed with meeting material needs that we overlook people's spiritual needs.
When Jesus healed people by touching them, it shows us that His love, mercy, and power, was so great that not only did He not become unclean by touching them, they became clean by His touch. We need to remain unpolluted by the sin around us, and instead be intentional about spreading His light into the darkness.
Tomorrow's Bible In a Year Passage passage: Isaiah 5-6, Mark 2